相同极性永磁体对感应式磁声磁粒子浓度成像过程影响的仿真

doi:10.19595/j.cnki.1000-6753.tces.210218

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摘要

感应式磁声磁粒子浓度成像（MACT-MI）是一种基于磁声耦合效应的磁性纳米粒子（MNPs）浓度成像新方法,为降低激励源幅值、增大磁声信号的信噪比,该文提出一种加入相同极性永磁体的MACT-MI新思路。根据Langevin顺磁理论,研究加入相同极性的永磁体后MACT-MI的电磁学与声学特性,进而对磁体系统进行设计,同时构建浓度渐变模型,采用多物理场仿真软件COMSOL对MACT-MI的物理过程进行求解,得到磁通密度、磁力和声压的二维分布及其对应的一维曲线。研究结果表明,加入相同极性永磁体后,MNPs受到的磁力更强,从而激发信噪比更大的磁声信号,有利于声信号的获取,在所设计的磁体系统激励下,MNPs产生的声压呈上下对称分布且方向相反,浓度均匀模型中声压的峰值出现在浓度边界处,浓度渐变模型声压的峰值出现在渐变中心处。研究结果可为成像装备的设计以及MACT-MI的后续实验乃至临床应用提供研究基础。

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	闫孝姮
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关键词 ：磁性纳米粒子, 相同极性永磁体, 感应式磁声磁粒子浓度成像, 磁力, 声压

Abstract：

Magneto-acoustic concentration tomography of magnetic nanoparticles (MNPs) with magnetic induction (MACT-MI) is a new method for concentration imaging of MNPs based on the magneto-acoustic coupling effect. To reduce the excitation source amplitude and increase the signal-to-noise ratio of the magneto-acoustic signal, a new idea was proposed in this paper: the same polarity as the permanent magnet was added in the MACT-MI. According to the Langevin paramagnetic theory, the electromagnetic and acoustic characteristics of MAT-MI after adding permanent magnets with the same polarity were studied, the magnet system was designed, and the concentration gradient model was established. By multi-physics simulation software COMSOL, the 2D distribution of magnetic flux density, magnetic force and sound pressure and the corresponding 1D curve were obtained, which clearly show the physical process of MAT-MI. This conclusion indicates that adding permanent magnets of the same polarity, MNPs receive stronger magnetic force and can obtain magneto-acoustic signals with a larger signal-to-noise ratio, which is conducive to the acquisition of acoustic signals. At the excitation of the magnet system, the sound pressure generated by MNPs is symmetrically distributed up and down and in opposite directions. At the uniform concentration model, the sound pressure peak appears at the concentration boundary, and the peak of the sound pressure of the concentration gradient model appears at the center of the gradient. The results can provide a research foundation for the design of imaging equipment, follow-up experiments and clinical applications of MACT-MI.

Key words： Magnetic nanoparticles the same polarity permanent magnet magneto-acoustic concentration tomography of magnetic nanoparticles with magnetic induction (MACT-MI) magnetic force sound pressure

收稿日期: 2021-02-19

PACS:

TM12

基金资助:

2019年辽宁省自然科学基金指导项目（2019-ZD-0039）和2020年辽宁省教育厅科学研究基础研究项目（LJ2020JCL003）资助

通讯作者: 李政兴男,1997年生,硕士研究生,研究方向为电磁探测与成像。E-mail: lizhengxing163@163.com

作者简介: 闫孝姮女,1984年生,博士,副教授,研究方向为电磁探测与成像。E-mail: xiaohengyan@163.com

引用本文:

闫孝姮, 李政兴, 潘也, 陈伟华. 相同极性永磁体对感应式磁声磁粒子浓度成像过程影响的仿真[J]. 电工技术学报, 2022, 37(8): 1926-1937. Yan Xiaoheng, Li Zhengxing, Pan Ye, Chen Weihua. Simulation of the Influence of Permanent Magnets of the Same Polarity on the Magneto-Acoustic Concentration Tomography of Magnetic Nanoparticles with Magnetic Induction Process. Transactions of China Electrotechnical Society, 2022, 37(8): 1926-1937.

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