Oxygen Concentration Effect on the Mass Transfer of Reactive Species of the Atmospheric-Pressure He/O2 Plasma in Aqueous Solution
Ding Yunhan1, Wang Xiaolong1, Tan Zhenyu1, Liu Yadi2
1. School of Electrical Engineering Shandong University Jinan 250061 China; 2. Institute of Electrical Engineering Chinese Academy of Sciences Beijing 100190 China
Abstract：Cold-temperature atmospheric plasma (CAP) has been successfully applied in biological engineering, such as sterilization, surgery and even cancer treatment. However, the biological tissue to be treated is usually covered with a layer of aqueous solution with a thickness of tens to hundreds of microns. Plasma action on the surface of biological tissues necessarily involves the mass transfer process of the active species generated by the plasma in aqueous solution. There are lots of experimental measurement techniques have been used to analyze the mass transfer process between plasma and water. However, due to the limited detection technology, it is difficult to obtain the concentration distribution of species in aqueous solution. Thus, we used numerical simulations to quantify the mass transfer of active species in aqueous solutions. Based on the one-dimensional diffusion-reaction model, the mass transfer process of active species produced in plasma from the gas phase region to the gas-liquid interface region and finally into the liquid phase region is investigated in this work by establishing the control equations and boundary conditions of liquid phase region. The generation of active species in the plasma is closely related to the oxygen volume in the discharge gas,so we analyzed the generation and consumption reactions of active species in aqueous solution by simulating 19 reactive oxygen species (ROS) and 84 main chemical reactions in the liquid phase region with the change of the oxygen volume fraction in the discharge gas (the range is 0.1%~5%), in order to study the penetration depth distribution of the five main ROSs (H2O2, O2-, HO2, O3, and OH) in liquid phase region under different conditions. According to the simulation, the change of oxygen volume in the discharge gas has an impact on the flux of active species generated by the plasma into the liquid phase region, which also affects the generation and consumption of the five main ROS in the aqueous solution. For H2O2, O2-, and HO2, all the generation, consumption, and net generation decrease with the increase of oxygen content, while for the OH and O3, all the generation, consumption, and net generation increase with increase of oxygen content. These processes finally results in the change of the species number density and penetration depth of the ROS. The following conclusions can be drawn from the simulation analysis: (1)The change of the oxygen content volume in the discharge gas affects the flux of related oxygen species and electrons into the liquid surface, and then affects the species number density concentration and penetration of the five ROSs in the aqueous solution depth. (2)The penetration depth of OH and O3 increases with the increase of oxygen volume, from a few μm to more than 20 μm within the range of oxygen volume considered, this depth makes it possible for these two species to act directly on some biological tissue. (3)The species number density of H2O2, O2-, and HO2 in aqueous solution decreases with the increase of oxygen volume, so their penetration depth also decreases, but they still remains above a considerable value of hundreds of microns. Therefore, the reduction of the penetration depth of the three particles has little effect on their biomedical applications.
丁蕴函, 王晓龙, 谭震宇, 刘亚迪. 大气压He/O2等离子体活性粒子在水溶液中传质的氧含量效应[J]. 电工技术学报, 2023, 38(11): 2977-2988.
Ding Yunhan, Wang Xiaolong, Tan Zhenyu, Liu Yadi. Oxygen Concentration Effect on the Mass Transfer of Reactive Species of the Atmospheric-Pressure He/O2 Plasma in Aqueous Solution. Transactions of China Electrotechnical Society, 2023, 38(11): 2977-2988.
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