基于矩阵式线圈的感应式磁声磁粒子浓度成像研究

doi:10.19595/j.cnki.1000-6753.tces.210959

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Abstract Magnetoacoustic concentration tomography of magnetic nanoparticles (MNPs) with magnetic induction (MACT-MI) is a new method for MNPs concentration tomography. To reduce the amplitude of the excitation current source and produce a more stable magnetoacoustic signal, MACT-MI system based on matrix coils was studied. Optimal design of matrix coils used the artificial fish swarm algorithm based on beetle antennae search algorithm (BAS-AFSA). According to the optimization results the physical process of MACT-MI was solved by using COMSOL and then the results were compared with the results of Maxwell coils. A concentration gradient model was also constructed based on the distribution of MNPs in the actual biological tissue environment, and both the magnetic force and sound pressure distribution in the region of interest (ROI) were obtained. The results show that the matrix coils designed in this paper can produce a more stable sound pressure signal and a more uniformly distributed gradient magnetic field with equal size under a smaller excitation. According to the constructed concentration gradient model, both the magnetic force and the width of the sound pressure wave of MNPs are proportional to the width of the gradient region, and the peak value of sound pressure is proportional to the concentration gradient in the gradient region. The results provide a prospective basis for the design of imaging equipment, the follow-up experiments and clinical applications of MACT-MI.

Key words： Magnetic nanoparticles with magnetic induction (MACT-MI) artificial fish swarm algorithm based on beetle antennae search algorithm matrix coils concentration gradient magnetic force sound pressure

Received: 30 June 2021

PACS:

TM12

Fund:This work is partially supported by the Natural Science Foundation of Liaoning Province (2019-ZD-0039) and the Basic Scientific Research Project of Liaoning Education Department (LJ2020JCL003).

Corresponding Authors: Li Zhengxing, born in 1997, postgraduate, research interests include electromagnetic detection and imaging.E-mail: lizhengxing@163.com

About author:: Yan Xiaoheng, born in 1984, PhD, associate professor, research interests include electromagnetic detection and imaging.E-mail: xiaohengyan@163.com

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Cite this article:

Yan Xiaoheng,Li Zhengxing,Sun Di等. Magnetoacoustic Concentration Tomography of Magnetic Nanoparticles with Magnetic Induction Based on Matrix Coil[J]. Transactions of China Electrotechnical Society, 2022, 37(17): 4269-4283.

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https://dgjsxb.ces-transaction.com/EN/10.19595/j.cnki.1000-6753.tces.210959 OR https://dgjsxb.ces-transaction.com/EN/Y2022/V37/I17/4269

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