多通道经颅磁刺激线圈阵列的驱动与控制

doi:10.19595/j.cnki.1000-6753.tces.170142

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Abstract Transcranial magnetic stimulation (TMS) is a non-invasive nerve stimulation technique that has been widely used in clinical treatment in recent years. Compared with traditional single-channel magnetic stimulation coil, multi-channel coil array has shown more attractive capacities to achieve multi-point synchronous stimulation, scanning stimulation, and flexible switch of various stimulation patterns. However, the driving and controlling methods of the multi-channel TMS require further investigations due to the design complexity of the driving circuits and the electromagnetic coupling of multi-coils. A driving and controlling circuit was designed based on the 4×4 straight-wire array in this paper. The driving circuit was designed to generate the pulse current, mainly consisting of one capacitor charging segment and eight discharging segments. The stimulating pattern, amplitude and repetitive frequency of the stimulating current could be flexibly adjusted through the controlling circuit. By theoretical calculation and experimental measurement, the effect of electromagnetic coupling on current was analyzed. The experimental results also illustrated the ability for achieving the adjustment of the repetitive frequency and stimulating pattern. The stimulating strength below the coil array (3cm) was theoretically proved exceeding the excitation threshold of brain cells.

Key words： Transcranial magnetic stimulation, multi-channel coil array, drive and control, electromagnetic coupling

Received: 13 February 2017 Published: 05 December 2017

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TM12

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	Li Jiangtao
	Cao Hui
	Zheng Minjun
	Zhao Zheng

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Li Jiangtao,Cao Hui,Zheng Minjun等. The Drive and Control of Multi-Channel Transcranial Magnetic Stimulation Coil Array[J]. Transactions of China Electrotechnical Society, 2017, 32(22): 158-165.

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https://dgjsxb.ces-transaction.com/EN/10.19595/j.cnki.1000-6753.tces.170142 OR https://dgjsxb.ces-transaction.com/EN/Y2017/V32/I22/158

[1] 董国亚, 汤志华, 等. 各向异性真实头模型下深部脑刺激电场分布[J]. 电工技术学报, 2015, 30(增刊2): 37-41.
Dong Guoya, Tang Zhihua, et al. Electric field distributions of deep brain stimulation based on anisotropic real head model[J]. Transactions of China Electrotechnical Society, 2015, 30(S2): 37-41.
[2] 田瑞, 逯迈. 高速动车组动力电缆对车厢内乘客的低频电磁暴露水平仿真及其健康评估[J]. 高电压技术, 2016, 42(8): 2540-2548.
Tian Rui, Lu Mai. Simulation and health assessment of low frequency electromagnetic exposure of power cables below the carriage of high-speed electric multiple units[J]. High Voltage Engineering, 2016, 42(8): 2540-2548.
[3] 郭磊, 王瑶, 于洪丽, 等. 基于近似熵的磁刺激穴位脑功能网络构建与分析[J]. 电工技术学报, 2015, 30(10): 31-38.
Guo Lei, Wang Yao, Yu Hongli, et al. Brain functional network based on approximate entropy of EEG under magnetic stimulation at acupuncture point[J]. Transactions of China Electrotechnical Society, 2015, 30(10): 31-38.
[4] Barker A T, Jalinous R, Freeston I L. Non-invasive magnetic stimulation of human motor cortex[J]. The Lancet, 1985, 325(8437): 1106-1107.
[5] 于阳, 李玥, 张广浩, 等. 适用于临床及动物试验的高频重复经颅磁刺激系统设计及其应用[J]. 高电压技术, 2013, 242(1): 181-187.
Yu Yang, Li Yue, Zhang Guanghao, et al. Design and Application of high frequency repetitive trans- cranial magnetic stimulation system for clinical and animal tests[J]. High Voltage Engineering, 2013, 242(1): 181-187.
[6] 李江涛, 郑敏军, 曹辉. 经颅磁刺激技术的研究进展[J]. 高电压技术, 2016, 42(4): 1168-1178.
Li Jiangtao, Zheng Minjun, Cao Hui. Research progress in transcranial magnetic stimulation tech- nology[J]. High Voltage Engineering, 2016, 42(4): 1168-1178.
[7] Ruohonen J, Ilmoniemi R J. Focusing and targeting of magnetic brain stimulation using multiple coils[J]. Medical and Biological Engineering and Computing, 1998, 36(3): 297-301.
[8] 郭明霞, 王学民. 多信道经颅磁刺激线圈阵列设计及场强分布计算[J]. 天津医科大学学报, 2001, 7(1): 38-40.
Guo Mingxia, Wang Xuemin. Design and field distribution calculation of the multi-channel trans- cranial magnetic stimulation coil array[J]. Journal of Tianjin Medical University, 2001, 7(1): 38-40.
[9] Han B H, Chun I K, Lee S C, et al. Multichannel magnetic stimulation system design considering mutual couplings among the stimulation coils[J]. IEEE Transactions on Biomedical Engineering, 2004, 51(5): 812-817.
[10] Jiang R, Jansen B H, Sheth B R, et al. Dynamic multi-channel TMS with reconfigurable coil[J]. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2013, 21(3): 370-375.
[11] 兰贞波, 文武, 阮江军, 等. 基于有限元法的干式变压器多物理场分析计算[J]. 高压电器, 2015, 51(8): 107- 113.
Lan Zhenbo, Wen Wu, Ruan Jiangjun, et al. Analysis of multi-physical field in ventilated dry-type transformer with FEM method[J]. High Voltage Apparatus, 2015, 51(8): 107-113.
[12] 徐肖伟, 钱国超, 邹德旭, 等. 不同模型下变压器绕组漏磁场及短路力的比对研究[J]. 高压电器, 2016, 52(5): 85-89, 95.
Xu Xiaowei, Qian Guochao, Zou Dexu, et al. Comparison research on leakage magnetic field and short-circuit force of transformer windings under different models[J]. High Voltage Apparatus, 2016, 52(5): 85-89, 95.
[13] Davey K, Riehl M. Designing transcranial magnetic stimulation systems[J]. IEEE Transactions on Magnetics, 2005, 41(3): 1142-1148.
[14] Davey K, Epstein C M. Magnetic stimulation coil and circuit design[J]. IEEE Transactions on Biomedical Engineering, 2000, 47(11): 1493-1499.
[15] 刘国强, 霍小林. 三层球模型经颅磁刺激感应电场研[J]. 中国生物医学工程学报, 2004, 23(1): 83-86.
Liu Guojiang, Huo Xiaolin. Induced electric field of the concentric three-shell spherical model in the TMS[J]. Chinese Journal of Biomedical Engineering, 2004, 23(1): 83-86.
[16] 任青华, 王英翘, 姚列英. 基于IGBT的大功率H桥快控电源控制策略[J]. 强激光与粒子束, 2016, 28(9): 120-124.
Ren Qinghua, Wang Yingqiao, Yao Lieying. Control strategy for high power H-bridge quick response power supply based on IGBT[J]. High Power Laser and Particle Beams, 2016, 28(9): 120-124.
[17] 郭永, 贺超, 陈国柱. 驱动脉冲边沿调制技术及其在开关尖峰抑制上的应用[J]. 中国电机工程学报, 2015, 35(6): 1482-1489.
Guo Yong, He Chao, Chen Guozhu. A technique on driving-pulse edge-modulation and its application in reducing the switching voltage spike of power electronic device[J]. Proceedings of the CSEE, 2015, 35(6): 1482-1489.
[18] 戴玲, 田书耘, 等. 脉冲功率晶闸管反向恢复特性[J]. 强激光与粒子束, 2016, 28(11): 133-137.
Dai Ling, Tian Shuyun, et al. Reverse recovery characteristics of pulse power thyristor[J]. High Power Laser and Particle Beams, 2016, 28(11): 133-137.
[19] 陈政宇, 余占清, 吕纲, 等. 基于IGCT串联的10kV直流混合断路器研究[J]. 中国电机工程学报, 2016, 36(2): 317-326.
Chen Zhengyu, Yu Zhanqing, Lü Gang, et al. Researches on 10kV DC hybrid circuit breaker based on IGCT series[J]. Proceedings of the CSEE, 2016, 36(2): 317-326.
[20] Hu Guangyue, Liang Yihan, Song Falun, et al. A 7 T pulsed magnetic field generator for magnetized laser plasma experiments[J]. Plasma Science and Techno- logy, 2015, 17(2): 134-140.
[21] Gu Jianwei, Zhang Cheng, Wang Ruixue, el al. Improvement of spatial uniformity of nanosecond- pulse diffuse discharges in a multi-needle-to-plane gap[J]. Plasma Science and Technology, 2016, 18(3): 230-235.