Polymerization of Stimuli-Responsive Hydrogels by Using a Cold Atmospheric Plasma Jet
Shi Fukun1, Guo Yuyi1, Wang Qun1, Juergen F. Kolb2, Zhuang Jie1
1. Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Sciences Suzhou 215163 China; 2. Leibniz Institute of Plasma Science and Technology Greifswald 17489 Germany
Abstract An atmospheric plasma jet (APPJ) was used to directly treat the mixture of (hydroxyethyl) methacrylate (HEMA) and 2-(diethylamino)ethyl methacrylate (DEAEMA) monomers to get stimuli-responsive hydrogels. The fabrication of plasma polymerized HEMA-co-DEAEMA (PPHD) hydrogels did not need crosslinkers or initiator agents. Analysis of X-ray photoelectron spectroscopy (XPS) revealed that PPHD hydrogels inherited functionalities of individual monomers. The calculation of the contact angle and surface energy indicated that PPHD hydrogels are hydrophilic. Impedance spectroscopy for PPHD hydrogels in different pH solutions revealed a reversible pH-response manner. In vitro cytotoxicity test showed a good biocompatibility for PPHD hydrogels, which could significantly enhance the adhesion and proliferation of osteoblast cells (MG-63).
Shi Fukun,Guo Yuyi,Wang Qun等. Polymerization of Stimuli-Responsive Hydrogels by Using a Cold Atmospheric Plasma Jet[J]. Transactions of China Electrotechnical Society, 2021, 36(15): 3147-3153.
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2021, Vol. 36 
