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| Temperature Field Optimization of Nano-Magnetic Fluid Hyperthermia Device |
| Hu Guanzhong, Yang Shiyou, Li Yuling |
| College of Electrical Engineering Zhejiang University Hangzhou 310027 China |
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Abstract Magnetic induction hyperthermia (MIH), based on the Neer relaxation heat generation mechanism of the magnetic medium in an alternating magnetic field, is an adjuvant treatment technology for tumor lesions. A precise temperature control of the hyperthermia region is essential in order to ensure a relatively desired therapeutic. In this paper, an automatic shape optimization procedure is implemented to acquire tumor lesion optimal temperature distribution produced by a uniform magnetic field generating device using magnetic-thermal coupled finite element analysis and multi-objective optimization algorithms. The effect of multi-injection and blood perfusion is considered. The simulation result shows that an appropriate device shape and injection point location can produce a relatively ideal temperature field distribution in the tumor hyperthermia region.
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Received: 11 October 2013
Published: 22 May 2014
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2013, Vol. 28 
