Electric Field Distributions of Deep Brain Stimulation Based on Anisotropic Real Head Model
Dong Guoya1, Tang Zhihua1, Han Tingyan2, Luo Yuhao1, Zhao Jun1
1. Province-Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability Hebei University of Technology Tianjin 300130 China;
2. Hebei University of Technology City College Tianjin 300132 China
The deep brain stimulation (DBS) effect using implantable neuron-stimulation systems has become an important symptomatic therapy in movement disorders such as Parkinson’s disease. This study presents a head finite element model of deep brain stimulation to examine the electric field distribution. The electrical field distributions of DBS are analyzed with an anisotropic real head model and comparisons are carried out between the isotropic and anisotropic brain models. The head model using a geometrically accurate model includes four layers, i.e., scalp, skull, CSF, and brain. The purpose of this study is to assess the impacts on electric distribution by incorporating brain anisotropy in a forward numerical model for DBS.
董国亚, 汤志华, 韩婷彦, 罗宇豪,赵军. 各向异性真实头模型下深部脑刺激电场分布[J]. 电工技术学报, 2015, 30(增刊2): 37-41.
Dong Guoya, Tang Zhihua, Han Tingyan, Luo Yuhao, Zhao Jun. Electric Field Distributions of Deep Brain Stimulation Based on Anisotropic Real Head Model. Transactions of China Electrotechnical Society, 2015, 30(增刊2): 37-41.
[1] Yousif N, Liu Xuguang. Investigating the depth electrode-brain interface in deep brain stimulation using finite element models with graded complexity in structure and solution[J]. Journal of Neuroscience Methods, 2009, 184(1): 142-151.
[2] Yousif N, Purswani N, Bayford R, et al. Evaluating the impact of the deep brain stimulation induced electric field on subthalamic neurons: A computa- tional modeling study[J]. Journal of Neuroscience Methods, 2010, 188(1): 105-112.
[3] 于超, 李刚, 李世民, 等. 深部脑刺激作用机制的探讨[J]. 生物物理学报, 2005, 21(5): 325-331.
Yu Chao, Li Gang, Li Shimin, et al. Uncovering the mechanism of deep brainstimulation[J]. Acta Biophy- sica Sinica, 2005, 21(5): 325-331.
[4] Wolters C H, Anwander A, Tricoce X, et al. Influence of tissue conductivity anisotropy on EEG/MEG field and return current computation in a realistic head model: a simulation and visualization study using high-resolution finite element modeling[J]. Neuroimage, 2006, 30(3): 813-826.
[5] Abascal J F, Arridge S R, Atkinson D, et al. Use of anisotropic modelling in electrical impedance tomo- graphy description of method and preliminary assess- ment of utility in imaging brain function in the adult human head[J]. Neuroimage, 2008, 43(2): 258-268.
[6] Gabran S, Saad J, Salama M, et al. Finite difference time domain (FDTD) modeling of implanted deep brain stimulation electrodes and brain tissue[C]//31st Annual International Conference of the IEEE EMBS Minneapolis, Minnesota, USA, 2009: 6485-6488.
[7] Choi C, Lee Yen Ting, Tsou Yi Lin. Modeling deep brain stimulation based on current steering scheme[J]. IEEE Transacetions on Magnetics, 2011, 47(5): 890- 893.
[8] 刘荣美, 汪友华, 张岩. 建筑结构中雷电流和磁场分布特性的频域有限元方法分析[J]. 电工技术学报, 2013, 28(2): 140-145. Liu Rongmei, Wang Youhua, Zhang Yan. Frequency domain finite element analysis of lightning current and magnetic field distribution characteristics in building structure[J]. Transactions of China Elec- trotechnical Society, 2013, 28(2): 140-145.
[9] Grant P, Lowery M. Effect of dispersive conductivity and permittivity in volume conductor models of deep brain stimulation[J]. IEEE Transacetions on Biomedical Engineering, 2010, 57(10): 2386-2393.
[10] 罗涛, 陈民铀, 曾灿. 电力电缆安全监测中温度场和电场数值关系分析[J]. 电力系统保护与控制, 2010, 38(5): 20-24. Luo Tao, Chen Minyou, Zeng Can. Study of numerical relationship between temperature and electric field in power cables safety monitoring[J]. Power System Protection and Control, 2010, 38(5): 20-24.
[11] 夏慧, 刘国强, 黄欣, 等. 基于互易定理的二维磁声电成像系统[J]. 电工技术学报, 2013, 28(7): 163-168. Xia Hui, Liu Guoqiang, Huang Xin, et al. 2D magneto- acousto-electrical tomography system based on reci- procity theorem[J]. Transactions of China Electro- technical Society, 2013, 28(7): 163-168.
2015, Vol. 30 
